Compound: Etoposide aglycone
MF
C29H32O13
MW
588.56
Function
dozens of chemotherapy regimens for a variety of malignancies
Basic Organisms
Podophyllum hexandrum
Precursor
Podophyllotoxin
Host
Nicotiana benthamiana
Synthesis Type
Complete biosynthesis
Downstream Gene
CYP
Pathway
Reference
Lau W, Sattely E S. Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone[J]. Science, 2015, 349(6253): 1224-1228.