Compound: Etoposide aglycone

MF

C29H32O13

MW

588.56

Function

dozens of chemotherapy regimens for a variety of malignancies

Basic Organisms

Podophyllum hexandrum

Precursor

Podophyllotoxin

Host

Nicotiana benthamiana

Synthesis Type

Complete biosynthesis

Downstream Gene

CYP

Pathway

pathway

Reference

Lau W, Sattely E S. Six enzymes from mayapple that complete the biosynthetic pathway to the etoposide aglycone[J]. Science, 2015, 349(6253): 1224-1228.