MF

C₃₀H₅₀O

MW

426.72

Function

treatment of inflammatory and autoimmune diseases, Alzheimer’s disease and cancer

Basic Organisms

Tripterygium wilfordii

Precursor

2,3-oxidosqualene

Host

Saccharomyces cerevisiae

Synthesis Type

Complete biosynthesis

Downstream Gene

OSC

Pathway

Reference

Zhou J, Hu T, Gao L, et al. Friedelane‐type triterpene cyclase in celastrol biosynthesis from Tripterygium wilfordii and its application for triterpenes biosynthesis in yeast[J]. New Phytologist, 2019, 223(2): 722-735.