MF

C₁₅H₁₀O₆

MW

286.24

Function

neuroprotective, neu- rotrophic and anti-amyloid properties, which makes it a promising therapeutic agent for neurodegenerative disorders such as Hunt- ington and Alzheimer diseases

Basic Organisms

universal

Precursor

resokaempferol

Host

Saccharomyces cerevisiae

Synthesis Type

Complete biosynthesis

Downstream Gene

FMO, CPR

Pathway

Reference

1. Rodriguez A, Strucko T, Stahlhut S G, et al. Metabolic engineering of yeast for fermentative production of flavonoids[J]. Bioresource Technology, 2017, 245: 1645-1654.
2. Stahlhut S G, Siedler S, Malla S, et al. Assembly of a novel biosynthetic pathway for production of the plant flavonoid fisetin in Escherichia coli[J]. Metabolic engineering, 2015, 31: 84-93.