Description

American pokeweed, Phytolacca americana, belongs to the Phytolaccaceae family of flowering plants. P. americana (pokeweed) is the most well-studied Phytolacca species due to its broad agricultural and medical applications. Pokeweed synthesizes PAP, an N-glycosidase and RIP that depurinates the conserved α-sarcin loop of large rRNAs. PAP exhibits antiviral activity against diverse plant and animal viruses.